Understanding the ACTH Stimulation Test- A Comprehensive Guide for Dog Owners_1

What is ACTH Stimulation Test for Dogs?

The ACTH stimulation test, also known as the Canine Adrenocorticotropic Hormone stimulation test, is a diagnostic procedure used to evaluate the function of the adrenal glands in dogs. The adrenal glands are vital organs located on top of the kidneys, responsible for producing a variety of hormones that regulate metabolism, immune response, and stress response. This test is commonly used to diagnose Cushing’s disease, a condition characterized by excessive cortisol production, and Addison’s disease, which is a deficiency of cortisol and aldosterone hormones.

The ACTH stimulation test involves measuring the levels of cortisol in a dog’s blood or urine before and after the administration of synthetic ACTH, a hormone that stimulates the adrenal glands to produce cortisol. By comparing the cortisol levels before and after the ACTH injection, veterinarians can determine if the adrenal glands are functioning properly or if there is an underlying disorder affecting them. This test is particularly useful in dogs with symptoms that may be indicative of adrenal gland dysfunction, such as increased thirst, appetite, and urination, or unexplained weight loss, lethargy, and muscle weakness.